For clinicians
Adding objective support to depression care
Supporting, not replacing, your judgement
LumetrixDx - Clinical Role
Supporting – not replacing – your judgement
In routine practice, assessment of depression relies on careful listening, structured questioning and experience. LumetrixDx has been developed to complement this work by providing a standardised, objective view of brain activity associated with depression.
Following validation and regulatory approval, LumetrixDx will offer:
Diagnostic support
Helping to confirm or clarify whether a person’s presentation is consistent with major depressive disorder, particularly when symptoms overlap with other conditions.Severity assessment and monitoring
Providing a stable reference point that can be tracked over time, alongside symptom scales and clinical impressions.Treatment optimisation
Baseline and early-change brain patterns can help predict and monitor treatment response, with the long-term goal of reducing trial-and-error.
At every stage, LumetrixDx is intended as a decision support tool. Clinical diagnosis and management decisions remain with the treating clinician.
How LumetrixDx is designed to fit into practice
A brief but effective addition to a standard assessment
A typical workflow:
Clinical assessment
You take a history, explore symptoms, use your preferred depression scales and consider differential diagnoses as usual.Short EEG recording
Non-invasive sensors are placed on the forehead to record several minutes of resting-state EEG focused on frontal brain regions linked with mood regulation.Automated analysis
The EEG is processed using validated algorithms. A short symptom questionnaire may also be completed as part of the assessment.Decision support output
You receive a concise report containing standardised scores, risk bands and interpretive comments, designed to be understandable at a glance.Shared decision-making
You integrate this information with the clinical picture and discuss options with the person in front of you.
Evidence and development
From research signal to clinical tool
LumetrixDx builds on a body of research suggesting that certain EEG patterns in frontal brain regions differ, on average, between people with major depressive disorder and healthy controls, and may change with treatment.
Our development programme includes:
Feasibility studies
Testing practicality, patient and clinician acceptability, data quality and initial algorithm performance in real clinical environments.Validation studies
Larger, multi-site studies designed to estimate sensitivity, specificity and AUC for key intended uses, and to test stability across sites and devices.Real-world implementation studies
Working with services to understand how LumetrixDx could be embedded into care pathways, what impact it has on decisions and outcomes, and what supports sustained use.
Safety, ethics and limitations
Using new tools responsibly
Depression is a complex, heterogeneous condition. No single test can capture every dimension of a person’s experience, and no algorithm is perfect.
LumetrixDx is designed around clear principles:
Non-invasive and low-risk
EEG recording is painless and does not involve any stimulation. Sensors simply record naturally occurring electrical activity at the scalp.Support, not verdicts
Outputs are framed as probabilities and patterns, not yes/no labels. We explicitly discourage use of the tool as a sole basis for diagnosis, treatment decisions or eligibility for services.Transparency about uncertainty
Reports will indicate uncertainty where appropriate and avoid deterministic language, especially around prognosis.Patient-centred communication
We provide suggested wording and support materials to help clinicians explain what the test does and does not mean, in ways that validate rather than dismiss people’s experiences.
Ethics approvals, data protection measures and risk management are integral to all of our research studies.
Purchase LumetrixDx for your clinic
Get in touch to purchase LumetrixDx for your clinic.
Collaborate with us
We are actively seeking:
Clinical sites interested in feasibility or validation studies
Individual clinicians willing to advise on workflow and usability
Partners with expertise in psychiatry, neurology or other depression services
If you would like to discuss potential collaboration or stay informed about upcoming studies, please contact us or register your interest using the form below.